[Antiphospholipid syndrome - an update on diagnosis and treatment.] Pneumonologia i alergologia polska : organ Polskiego Towarzystwa Ftyzjopneumonologicznego, Polskiego Towarzystwa Alergologicznego, i Instytutu Gruzlicy i Chorob Pluc [Pneumonol Alergol Pol] Journal article | | Title | [Antiphospholipid syndrome - an update on diagnosis and treatment.] | | Author(s) | Szturmowicz M | | Source | Pneumonol Alergol Pol 2009; 77(5):460-468. | | Abstract | Antiphospholipid syndrome (APS) was described by Hughes et al in 1986 and then by Harris et al in 1987. The symptoms of disease are related to the presence of autoantibodies directed against plasma and serum proteins that form complexes with phospholipids of cell membranes. The immunologic process involving vascular endothelium, thrombocytes and coagulation factors is responsible for enhancement of procoagulation mechanisms and as a result - venous and arterial thrombosis. Actual criteria of recognition of APS were published in 2006 as a result of 11(th) International Congress on Antiphospholipid Antibodies which was taking place in 2004 in Sydney. Multiorgan symptoms of disease, criteria of recognition and methods of treatment were discussed in the present paper. | | Language | POL | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19890826 |
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